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Description
CD300b/LMIR5/CD300LB Fc Chimera Protein, MouseProduct Specification Species Mouse Synonyms CD300b Protein, Human; CLM 7 Protein, Human; CLM7 Protein, Human; CMRF35 A2 Protein, Human; IREM 3 Protein, Human; IREM3 Protein, Human; TREM 5 Protein, Human; TREM5 Protein, Human Accession Q3U497 Amino Acid Sequence Ile18 Tyr157, with C hIgG Fc Expression System HEK293 Molecular Weight 52 64kDa (Reducing) Purity 95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Physical Appearance Lyophilized
Product Specification
| Species | Mouse |
| Synonyms | CD300b Protein, Human; CLM-7 Protein, Human; CLM7 Protein, Human; CMRF35-A2 Protein, Human; IREM-3 Protein, Human; IREM3 Protein, Human; TREM-5 Protein, Human; TREM5 Protein, Human |
| Accession | Q3U497 |
| Amino Acid Sequence | Ile18-Tyr157, with C-hIgG Fc |
| Expression System | HEK293 |
| Molecular Weight | 52-64kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4, 5% trehalose |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1.Journal List Cell Death Differ v.21(11); 2014 Nov PMC4211373. |
Background
The CD300 receptor family members are a group of molecules that modulate a variety of immune cell processes. The CD300 receptor family consists of members with activating and inhibitory capabilities mainly expressed on the surface of immune cells. LMIR5, also known as CD300b, CD300LB, CLM-7, and IREM-3, is a glycoprotein member of the immunoglobulin superfamily. Human LMIR5 consists of a 134 amino acid (aa) extracellular domain (ECD) with one Ig-like V-type domain, a 21 amino acid (aa) transmembrane segment, and a 29 aa cytoplasmic domain. Studies have shown that CD300b recognizes PS as a ligand and regulates phagocytosis of apoptotic cells through DAP12 signaling pathway.
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4.6 ★★★★★
Based on 1419 reviews
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Product Reviews
★★★★★ 5
Dries clear, moisturizing, silky, great value
Size: 5 Fl Oz (Pack of 1), Style: SPF 50
I have fair to light combination skin. I use this on my body, but not my face. It goes on very thick and white, but sinks into the skin lightning fast (within just a few seconds), and it becomes completely invisible. It leaves my skin moisturized and looking and feeling silky. Best body sunscreen I've ever tried. And I love that it is water resistant! I find it too heavy and moisturizing to use on my face, but people with dry skin would probably love it for the face, too. I imagine it would be fantastic for them under makeup. The price per ounce is very reasonable, making it a great value.
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Reviewed in the United States on June 5, 2026
★★★★★ 5
Reliable Sun Protection for Active Days!
Size: 3 Fl Oz (Pack of 1), Style: SPF 50
Coppertone SPORT SPF 50 is my go-to sunscreen for outdoor activities. It’s lightweight, non-greasy, and stays on even when I’m sweating or swimming. The broad-spectrum formula protects against both UVA and UVB rays, giving me peace of mind during long hours in the sun.
The 3 fl oz size is perfect for carrying in a gym bag, backpack, or beach tote, making it easy to reapply throughout the day. It absorbs quickly and doesn’t leave a sticky residue, which is great for sports or active adventures.
Highly recommend for anyone who wants effective, durable sun protection without sacrificing comfort or mobility!
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Reviewed in the United States on November 21, 2025
★★★★★ 4
IT does protect from the sun.
Size: 5 Fl Oz (Pack of 1), Style: SPF 50
It protects from the sun without a doubt and lasts well. The downsides are that it leaves a greasy and "white" residue that no matter how much you rub it in.....it stays there. I use it when I am working outside and not planning on going anywhere anytime soon.
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Reviewed in the United States on May 20, 2026
★★★★★ 5
Fabulous
Size: 7 Fl Oz (Pack of 1), Style: SPF 50
Fabulous. Nice size bottle.
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Reviewed in the United States on May 24, 2026
★★★★★ 5
Great Sunscreen
Size: 7 Fl Oz (Pack of 1), Style: SPF 50
I cannot sing enough praises for Coppertone SPORT Sunscreen SPF 50 Lotion! This sunscreen is an absolute game-changer for anyone who loves outdoor activities. Here's why I think it deserves five stars:
Effective Protection: Whether I'm hiking, swimming, or playing beach volleyball, I trust Coppertone SPORT to keep my skin shielded from harmful UV rays. The SPF 50 protection gives me the confidence to enjoy the sun without worrying about sunburn.
Water Resistance: One of the standout features of this sunscreen is its water-resistant formula. It stays put even during sweaty workouts or dips in the pool, ensuring continuous protection throughout all my outdoor adventures.
Non-Greasy Formula: Unlike some other sunscreens that leave a greasy residue, Coppertone SPORT absorbs quickly into the skin, leaving it feeling smooth and hydrated without any stickiness. It's perfect for those who dislike the heavy feeling of traditional sunscreens.
Long-Lasting: I appreciate how long-lasting this sunscreen is. I can apply it in the morning before heading out for a day of activities, and it provides reliable protection for hours on end, saving me the hassle of frequent reapplication.
Suitable for Active Lifestyles: As someone with an active lifestyle, I need a sunscreen that can keep up with me. Coppertone SPORT ticks all the boxes with its durable and sweat-resistant formula, allowing me to focus on enjoying my time outdoors without constantly worrying about sun protection.
Overall, Coppertone SPORT Sunscreen SPF 50 Lotion has become a staple in my outdoor gear arsenal. It's dependable, effective, and comfortable to wear, making it a must-have for anyone who loves to stay active under the sun. I highly recommend it to fellow outdoor enthusiasts!
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Reviewed in the United States on April 20, 2024
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