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Description
Alexa Fluor® 647 Rat Anti-Mouse CD317 Antibody (S-3340)Product Specification Host Rat Antigen BST2 Synonyms Bone marrow stromal antigen 2; BST 2; HM1. 24 antigen; CD317; Bst2 Location Cell membrane Accession Q8R2Q8 Clone Number S 3340 Antibody Type Rat mAb Isotype IgG2b,k Application FCM Reactivity Ms Positive Sample C57BL 6 mouse splenocytes Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 647 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability &
Product Specification
| Host | Rat |
| Antigen | BST2 |
| Synonyms | Bone marrow stromal antigen 2; BST-2; HM1.24 antigen; CD317; Bst2 |
| Location | Cell membrane |
| Accession | Q8R2Q8 |
| Clone Number | S-3340 |
| Antibody Type | Rat mAb |
| Isotype | IgG2b,k |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | C57BL/6 mouse splenocytes |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Alexa Fluor® 647 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1.25μl per million cells in 100μl volume | Ms |
Background
CD317 is a type of protein that plays significant roles in various biological processes. It is a type II transmembrane protein mainly expressed on the surface of cells such as fibroblasts, endothelial and cells some immune cells. One of its key functions is in the regulation of cell proliferation and differentiation. For example, in the bone marrow microenvironment, CD137 protein can influence the growth and development of hematopoietic cells by interacting with other molecules. Moreover, it is involved in the immune response. It can affect the activation and function of immune cells like T cells and B cells, thus participating in the regulation of the body's immune defense mechanism. Additionally, CD137 protein has been found to be associated with some diseases. Abnormal expression of CD137 protein may be related to the occurrence and development of certain cancers and autoimmune diseases. Therefore, research on CD137 protein is of great importance for understanding the mechanisms of cell biology and disease pathogenesis.
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